Finding nascent proteins the right home
Cells must deliver the thousands of polypeptides they synthesize every minute to various specific subcellular locations. Precisely how this happens has been a topic of intense research, and some controversy, for the past 20 years, as critical components of the translation and translocation machineri...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
10 Apr 2015
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| In: |
Science
Year: 2015, Volume: 348, Issue: 6231, Pages: 182-183 |
| ISSN: | 1095-9203 |
| DOI: | 10.1126/science.aab1335 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1126/science.aab1335 Verlag, lizenzpflichtig, Volltext: https://science.sciencemag.org/content/348/6231/182 
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| Author Notes: | by Günter Kramer, D. Lys Guilbride, Bernd Bukau |
| Summary: | Cells must deliver the thousands of polypeptides they synthesize every minute to various specific subcellular locations. Precisely how this happens has been a topic of intense research, and some controversy, for the past 20 years, as critical components of the translation and translocation machineries - ribosomes and the signal recognition particle (SRP) - do not confer full target discrimination. |
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| Item Description: | Gesehen am 24.07.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1095-9203 |
| DOI: | 10.1126/science.aab1335 |