Impact of multifocal or multicentric disease on surgery and locoregional, distant and overall survival of 6,134 breast cancer patients treated with neoadjuvant chemotherapy

The impact of tumor focality on type of surgery, local recurrence rate, and survival after neoadjuvant chemotherapy (NACT) for breast cancer is not fully understood. This study aimed to compare local recurrence-free survival (LRFS), disease-free survival (DFS), and overall survival (OS) according to...

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Main Authors: Ataseven, Beyhan (Author) , Lederer, Bianca (Author) , Blohmer, Jens-Uwe (Author) , Denkert, Carsten (Author) , Gerber, Bernd (Author) , Heil, Jörg (Author) , Kühn, Thorsten (Author) , Kümmel, Sherko (Author) , Rezai, Mahdi (Author) , Loibl, Sibylle (Author) , Minckwitz, Gunter von (Author)
Format: Article (Journal)
Language:English
Published: 2015
In: Annals of surgical oncology
Year: 2014, Volume: 22, Issue: 4, Pages: 1118-1127
ISSN:1534-4681
DOI:10.1245/s10434-014-4122-7
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1245/s10434-014-4122-7
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Author Notes:Beyhan Ataseven, Bianca Lederer, Jens U. Blohmer, Carsten Denkert, Bernd Gerber, Jörg Heil, Thorsten Kühn, Sherko Kümmel, Mahdi Rezai, Sibylle Loibl, and Gunter von Minckwitz
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Summary:The impact of tumor focality on type of surgery, local recurrence rate, and survival after neoadjuvant chemotherapy (NACT) for breast cancer is not fully understood. This study aimed to compare local recurrence-free survival (LRFS), disease-free survival (DFS), and overall survival (OS) according to focality stratified by type of surgery and pathologic complete response (pCR), with a focus on breast conservation.
Item Description:Published: 09 October 2014
Gesehen am 28.07.2020
Physical Description:Online Resource
ISSN:1534-4681
DOI:10.1245/s10434-014-4122-7