miFRame: analysis and visualization of miRNA sequencing data in neurological disorders

While in the past decades nucleic acid analysis has been predominantly carried out using quantitative low- and high-throughput approaches such as qRT-PCR and microarray technology, next-generation sequencing (NGS) with its single base resolution is now frequently applied in DNA and RNA testing. Espe...

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Main Authors: Backes, Christina (Author) , Haas, Jan (Author) , Leidinger, Petra (Author) , Frese, Karen S. (Author) , Grossmann, Thomas (Author) , Ruprecht, Klemens (Author) , Meder, Benjamin (Author) , Meese, Eckart (Author) , Keller, Andreas (Author)
Format: Article (Journal)
Language:English
Published: 14 July 2015
In: Journal of translational medicine
Year: 2015, Volume: 13, Pages: 1-12
ISSN:1479-5876
DOI:10.1186/s12967-015-0594-x
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12967-015-0594-x
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Author Notes:Christina Backes, Jan Haas, Petra Leidinger, Karen Frese, Thomas Großmann, Klemens Ruprecht, Benjamin Meder, Eckart Meese, and Andreas Keller
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Summary:While in the past decades nucleic acid analysis has been predominantly carried out using quantitative low- and high-throughput approaches such as qRT-PCR and microarray technology, next-generation sequencing (NGS) with its single base resolution is now frequently applied in DNA and RNA testing. Especially for small non-coding RNAs such as microRNAs there is a need for analysis and visualization tools that facilitate interpretation of the results also for clinicians.
Item Description:Gesehen am 29.07.2020
Physical Description:Online Resource
ISSN:1479-5876
DOI:10.1186/s12967-015-0594-x