miFRame: analysis and visualization of miRNA sequencing data in neurological disorders

While in the past decades nucleic acid analysis has been predominantly carried out using quantitative low- and high-throughput approaches such as qRT-PCR and microarray technology, next-generation sequencing (NGS) with its single base resolution is now frequently applied in DNA and RNA testing. Espe...

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Hauptverfasser: Backes, Christina (VerfasserIn) , Haas, Jan (VerfasserIn) , Leidinger, Petra (VerfasserIn) , Frese, Karen S. (VerfasserIn) , Grossmann, Thomas (VerfasserIn) , Ruprecht, Klemens (VerfasserIn) , Meder, Benjamin (VerfasserIn) , Meese, Eckart (VerfasserIn) , Keller, Andreas (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 14 July 2015
In: Journal of translational medicine
Year: 2015, Jahrgang: 13, Pages: 1-12
ISSN:1479-5876
DOI:10.1186/s12967-015-0594-x
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12967-015-0594-x
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Verfasserangaben:Christina Backes, Jan Haas, Petra Leidinger, Karen Frese, Thomas Großmann, Klemens Ruprecht, Benjamin Meder, Eckart Meese, and Andreas Keller
Beschreibung
Zusammenfassung:While in the past decades nucleic acid analysis has been predominantly carried out using quantitative low- and high-throughput approaches such as qRT-PCR and microarray technology, next-generation sequencing (NGS) with its single base resolution is now frequently applied in DNA and RNA testing. Especially for small non-coding RNAs such as microRNAs there is a need for analysis and visualization tools that facilitate interpretation of the results also for clinicians.
Beschreibung:Gesehen am 29.07.2020
Beschreibung:Online Resource
ISSN:1479-5876
DOI:10.1186/s12967-015-0594-x