Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions

Cryo-EM analysis of a bacterial SRP reveals that, differently from eukaryotic SRP, it interacts with the ribosome via contacts between the 6S RNA and the 23S rRNA to mediate translational slowdown.

Saved in:

Bibliographic Details
Main Authors:	Beckert, Bertrand (Author) , Kedrov, Alexej (Author) , Sohmen, Daniel (Author) , Kempf, Georg (Author) , Wild, Klemens (Author) , Sinning, Irmgard (Author) , Stahlberg, Henning (Author) , Wilson, Daniel (Author) , Beckmann, Roland (Author)
Format:	Article (Journal)
Language:	English
Published:	07 September 2015
In:	Nature structural & molecular biology Year: 2015, Volume: 22, Issue: 10, Pages: 767-773
ISSN:	1545-9985
DOI:	10.1038/nsmb.3086
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nsmb.3086 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nsmb.3086
Author Notes:	Bertrand Beckert, Alexej Kedrov, Daniel Sohmen, Georg Kempf, Klemens Wild, Irmgard Sinning, Henning Stahlberg, Daniel N. Wilson, Roland Beckmann

Description
Summary:	Cryo-EM analysis of a bacterial SRP reveals that, differently from eukaryotic SRP, it interacts with the ribosome via contacts between the 6S RNA and the 23S rRNA to mediate translational slowdown.
Item Description:	Gesehen am 04.08.2020
Physical Description:	Online Resource
ISSN:	1545-9985
DOI:	10.1038/nsmb.3086