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A multifactorial histopathologic score for the prediction of prognosis of resected esophageal adenocarcinomas after neoadjuvant chemotherapy

For esophageal adenocarcinoma treated with neoadjuvant chemotherapy, postoperative staging classifications initially developed for non-pretreated tumors may not accurately predict prognosis. We tested whether a multifactorial TNM-based histopathologic prognostic score (PRSC), which additionally appl...

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Bibliographic Details
Main Authors: Langer, Rupert (Author) , Peters, Leila (Author) , Büchler, Markus W. (Author) , Weichert, Wilko (Author) , Ott, Katja (Author)
Format: Article (Journal)
Language:English
Published: 2014
In: Annals of surgical oncology
Year: 2013, Volume: 21, Issue: 3, Pages: 915-921
ISSN:1534-4681
DOI:10.1245/s10434-013-3410-y
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1245/s10434-013-3410-y
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Author Notes:Rupert Langer, Karen Becker, Inti Zlobec, Ralf Gertler, Leila Sisic, Markus Büchler, Florian Lordick, Julia Slotta-Huspenina, Wilko Weichert, Heinz Höfler, Marcus Feith, and Katja Ott
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Summary:For esophageal adenocarcinoma treated with neoadjuvant chemotherapy, postoperative staging classifications initially developed for non-pretreated tumors may not accurately predict prognosis. We tested whether a multifactorial TNM-based histopathologic prognostic score (PRSC), which additionally applies to tumor regression, may improve estimation of prognosis compared with the current Union for International Cancer Control/American Joint Committee on Cancer (UICC) staging system.
Item Description:Published: 27 November 2013
Gesehen am 12.08.2020
Physical Description:Online Resource
ISSN:1534-4681
DOI:10.1245/s10434-013-3410-y

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