Individual and joint contributions of genetic and methylation risk scores for enhancing lung cancer risk stratification: data from a population-based cohort in Germany
Risk stratification for lung cancer (LC) screening is so far mostly based on smoking history. This study aimed to assess if and to what extent such risk stratification could be enhanced by additional consideration of genetic risk scores (GRSs) and epigenetic risk scores defined by DNA methylation.
Gespeichert in:
| Hauptverfasser: | , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
18 June 2020
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| In: |
Clinical epigenetics
Year: 2020, Jahrgang: 12 |
| ISSN: | 1868-7083 |
| DOI: | 10.1186/s13148-020-00872-y |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13148-020-00872-y
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| Verfasserangaben: | Haixin Yu, Janhavi R. Raut, Ben Schöttker, Bernd Holleczek, Yan Zhang and Hermann Brenner |
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| 520 | |a Risk stratification for lung cancer (LC) screening is so far mostly based on smoking history. This study aimed to assess if and to what extent such risk stratification could be enhanced by additional consideration of genetic risk scores (GRSs) and epigenetic risk scores defined by DNA methylation. | ||
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