Unusual acid- and base-catalyzed C-N bond formation approach through reaction of chromonyl Meldrum’s acid and nitrogen binucleophiles
<p>Reaction of chromonyl Meldrum’s acid and N-substituted 2-aminobenzamides was studied in the presence of acidic and basic catalysts. The use of methanesulfonic acid as a catalyst in this reaction led to the synthesis of chromonyl quinazolinones through employing Meldrum’s acid as a carbon le...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2016
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| In: |
Synlett
Year: 2015, Volume: 27, Issue: 05, Pages: 782-788 |
| ISSN: | 1437-2096 |
| DOI: | 10.1055/s-0035-1560383 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-0035-1560383 Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1560383 
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| Author Notes: | Saeed Balalaie, Hamid Reza Bijanzadeh, Saber Mehrparvar, Frank Rominger |
| Summary: | <p>Reaction of chromonyl Meldrum’s acid and N-substituted 2-aminobenzamides was studied in the presence of acidic and basic catalysts. The use of methanesulfonic acid as a catalyst in this reaction led to the synthesis of chromonyl quinazolinones through employing Meldrum’s acid as a carbon leaving group. However, in the presence of basic catalyst, this reaction gave functionalized 2-pyridones.</p> |
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| Item Description: | Published online: 30.11.2015 Gesehen am 19.08.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1437-2096 |
| DOI: | 10.1055/s-0035-1560383 |