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Disseminated tumor cells as a monitoring tool for adjuvant therapy in patients with primary breast cancer

The presence of disseminated tumor cells (DTC) in the bone marrow (BM) of early breast cancer patients at initial surgery as well as during follow-up predicts an unfavorable outcome. This study aimed to assess whether adjuvant systemic therapy has the ability to eradicate DTC and to determine the cl...

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Main Authors: Gruber, Ines (Author) , Fehm, Tanja (Author) , Taran, Florin Andrei (Author) , Wallwiener, Markus (Author) , Hahn, Markus (Author) , Wallwiener, Diethelm (Author) , Krawzyck, Natalia (Author) , Hoffmann, Jürgen (Author) , Hartkopf, Andreas Daniel (Author)
Format: Article (Journal)
Language:English
Published: 20 February 2014
In: Breast cancer research and treatment
Year: 2014, Volume: 144, Issue: 2, Pages: 353-360
ISSN:1573-7217
DOI:10.1007/s10549-014-2853-6
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s10549-014-2853-6
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007%2Fs10549-014-2853-6
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Author Notes:Ines Gruber, Tanja Fehm, Florin Andrei Taran, Markus Wallwiener, Markus Hahn, Diethelm Wallwiener, Natalia Krawzyck, Juergen Hoffmann, Andreas Daniel Hartkopf
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Summary:The presence of disseminated tumor cells (DTC) in the bone marrow (BM) of early breast cancer patients at initial surgery as well as during follow-up predicts an unfavorable outcome. This study aimed to assess whether adjuvant systemic therapy has the ability to eradicate DTC and to determine the clinical impact of DTC-persistence.
Item Description:Gesehen am 21.08.2020
Physical Description:Online Resource
ISSN:1573-7217
DOI:10.1007/s10549-014-2853-6

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