Synthesis of functionalized chromones through sequential reactions in aqueous media

An efficient sequential four-component reaction of chromone carbaldehydes, Meldrum's acid, 4-hydroxyl coumarin or 6-methyl-4-hydroxyl-pyrone and primary alcohols is reported which leads to 5a-i in aqueous media. Replacing the primary alcohol with isopropyl alcohol and tert-butyl alcohol results...

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Hauptverfasser: Mehrparvar, Saber (VerfasserIn) , Balalaie, Saeed (VerfasserIn) , Rabbanizadeh, Mahnaz (VerfasserIn) , Rominger, Frank (VerfasserIn) , Ghabraie, Elmira (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 29 May 2014
In: Organic & biomolecular chemistry
Year: 2014, Jahrgang: 12, Heft: 30, Pages: 5757-5765
ISSN:1477-0539
DOI:10.1039/C4OB00618F
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1039/C4OB00618F
Verlag, lizenzpflichtig, Volltext: https://pubs.rsc.org/en/content/articlelanding/2014/ob/c4ob00618f
Volltext
Verfasserangaben:Saber Mehrparvar, Saeed Balalaie, Mahnaz Rabbanizadeh, Frank Rominger and Elmira Ghabraie
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Zusammenfassung:An efficient sequential four-component reaction of chromone carbaldehydes, Meldrum's acid, 4-hydroxyl coumarin or 6-methyl-4-hydroxyl-pyrone and primary alcohols is reported which leads to 5a-i in aqueous media. Replacing the primary alcohol with isopropyl alcohol and tert-butyl alcohol results in different products 10 and 11. The environmentally friendly features, good to high yields and easy work-up are advantages of this approach.
Beschreibung:Gesehen am 24.08.2020
Beschreibung:Online Resource
ISSN:1477-0539
DOI:10.1039/C4OB00618F