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The bidirectional tumor: mesenchymal stromal cell interaction promotes the progression of head and neck cancer

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Mesenchymal stromal cells (MSC) are an integral cellular component of the tumor microenvironment. Nevertheless, very little is known about MSC originating from human malignant tissue and modulation of these cells by tumor-derived factors. The aim of this study was to isolate and characterize MSC fro...

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Main Authors: Kansy, Benjamin Alexander (Author) , Dißmann, Philip A. (Author) , Hemeda, Hatim (Author) , Bruderek, Kirsten (Author) , Westerkamp, Anna M. (Author) , Jagalski, Vivien (Author) , Schuler, Patrick (Author) , Kansy, Julia Katharina (Author) , Lang, Stephan (Author) , Dumitru, Claudia A. (Author) , Brandau, Sven (Author)
Format: Article (Journal)
Language:English
Published: 12 August 2014
In: Stem cell research & therapy
Year: 2014, Volume: 5, Pages: 1-10
ISSN:1757-6512
DOI:10.1186/scrt484
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/scrt484
Verlag, lizenzpflichtig, Volltext: https://stemcellres.biomedcentral.com/articles/10.1186/scrt484
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Author Notes:Benjamin A. Kansy, Philip A. Dißmann, Hatim Hemeda, Kirsten Bruderek, Anna M. Westerkamp, Vivien Jagalski, Patrick Schuler, Katinka Kansy, Stephan Lang, Claudia A. Dumitru and Sven Brandau
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Summary:Mesenchymal stromal cells (MSC) are an integral cellular component of the tumor microenvironment. Nevertheless, very little is known about MSC originating from human malignant tissue and modulation of these cells by tumor-derived factors. The aim of this study was to isolate and characterize MSC from head and neck squamous cell carcinoma (HNSCC) and to investigate their interaction with tumor cells.
Item Description:Gesehen am 25.08.2020
Physical Description:Online Resource
ISSN:1757-6512
DOI:10.1186/scrt484

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