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Significance of histology in determining management of lesions regrowing after radiosurgery

Brain metastases treated with stereotactic radiosurgery may show delayed enlargement on post-treatment imaging that is of ambiguous etiology. Histopathologic interpretation of brain specimens is often challenging due to the presence of significant radiation effects admixed with irradiated residual t...

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Main Authors: Nath, Sameer (Author) , Sheridan, Alison D. (Author) , Rauch, Philipp (Author) , Yu, James B. (Author) , Minja, Frank J. (Author) , Vortmeyer, Alexander O. (Author) , Chiang, Veronica L. (Author)
Format: Article (Journal)
Language:English
Published: 7 February 2014
In: Journal of neuro-oncology
Year: 2014, Volume: 117, Issue: 2, Pages: 303-310
ISSN:1573-7373
DOI:10.1007/s11060-014-1389-2
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s11060-014-1389-2
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007%2Fs11060-014-1389-2
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Author Notes:Sameer K. Nath, Alison D. Sheridan, Philipp J. Rauch, James B. Yu, Frank J. Minja, Alexander O. Vortmeyer, Veronica L. Chiang
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Summary:Brain metastases treated with stereotactic radiosurgery may show delayed enlargement on post-treatment imaging that is of ambiguous etiology. Histopathologic interpretation of brain specimens is often challenging due to the presence of significant radiation effects admixed with irradiated residual tumor of indeterminate viability. The purpose of this study was to assess the impact of histologic findings on clinical outcomes following resection of these lesions.
Item Description:Gesehen am 25.08.2020
Physical Description:Online Resource
ISSN:1573-7373
DOI:10.1007/s11060-014-1389-2

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