Metal-free, visible-light-enabled direct C3-H arylation of anthranils

An eosin Y disodium salt-catalyzed photoredox C-H arylation of anthranils is reported. A variety of aryl diazonium tetrafluoroborates were used as aryl sources, providing the C3 cross-coupled products. The in situ generated reactive radicals were trapped by anthranils, providing an alternative metho...

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Bibliographic Details
Main Authors: Adak, Tapas (Author) , Hu, Chao (Author) , Rudolph, Matthias (Author) , Li, Jun (Author) , Hashmi, A. Stephen K. (Author)
Format: Article (Journal) Editorial
Language:English
Published: July 7, 2020
In: Organic letters
Year: 2020, Volume: 22, Issue: 14, Pages: 5640-5644
ISSN:1523-7052
DOI:10.1021/acs.orglett.0c01999
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1021/acs.orglett.0c01999
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Author Notes:Tapas Adak, Chao Hu, Matthias Rudolph, Jun Li, and A. Stephen K. Hashmi
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Summary:An eosin Y disodium salt-catalyzed photoredox C-H arylation of anthranils is reported. A variety of aryl diazonium tetrafluoroborates were used as aryl sources, providing the C3 cross-coupled products. The in situ generated reactive radicals were trapped by anthranils, providing an alternative method to transition-metal-catalyzed C-H arylations of anthranils. Gold-catalyzed downstream transformations demonstrate the synthetic potential of these valuable building blocks.
Item Description:Gesehen am 25.08.2020
Physical Description:Online Resource
ISSN:1523-7052
DOI:10.1021/acs.orglett.0c01999