Open, randomized, multi-center phase II study comparing efficacy and tolerability of Erlotinib vs. Carboplatin/Vinorelbin in elderly patients (>70 years of age) with untreated non-small cell lung cancer
Targeting the epidermal-growth-factor-receptor (EGFR) in non-small cell lung cancer (NSCLC) is an established treatment option with less toxicity compared to conventional chemotherapy. This study was undertaken to determine whether Erlotinib is non-inferior compared to chemotherapy as a first-line t...
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| Hauptverfasser: | , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
26 January 2014
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| In: |
Lung cancer
Year: 2014, Jahrgang: 84, Heft: 1, Pages: 62-66 |
| ISSN: | 1872-8332 |
| DOI: | 10.1016/j.lungcan.2014.01.024 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.lungcan.2014.01.024 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0169500214000609 |
| Verfasserangaben: | D.F. Heigener, K.M. Deppermann, J. v. Pawel, J.R. Fischer, C. Kortsik, S. Bohnet, M. v. Eiff, W. Koester, M. Thomas, P.A. Schnabel, M. Reck |
| Zusammenfassung: | Targeting the epidermal-growth-factor-receptor (EGFR) in non-small cell lung cancer (NSCLC) is an established treatment option with less toxicity compared to conventional chemotherapy. This study was undertaken to determine whether Erlotinib is non-inferior compared to chemotherapy as a first-line therapy in unselected elderly patients. |
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| Beschreibung: | Gesehen am 26.08.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1872-8332 |
| DOI: | 10.1016/j.lungcan.2014.01.024 |