Coaxiality of Foxb1- and parvalbumin-expressing neurons in the lateral hypothalamic PV1-nucleus
In the ventrolateral hypothalamus, the PV1-nucleus is defined by its population of parvalbumin-expressing neurons. During embryogenesis, the ventrolateral hypothalamus is colonized also by Foxb1-expressing neurons. In adult Foxb1-EGFP mice, many immunofluorescent neurons were found within the region...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
14 February 2014
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| In: |
Neuroscience letters
Year: 2014, Volume: 566, Pages: 111-114 |
| ISSN: | 1872-7972 |
| DOI: | 10.1016/j.neulet.2014.02.028 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.neulet.2014.02.028 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0304394014001323 
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| Author Notes: | Alessandro Bilella, Gonzalo Alvarez-Bolado, Marco R. Celio |
| Summary: | In the ventrolateral hypothalamus, the PV1-nucleus is defined by its population of parvalbumin-expressing neurons. During embryogenesis, the ventrolateral hypothalamus is colonized also by Foxb1-expressing neurons. In adult Foxb1-EGFP mice, many immunofluorescent neurons were found within the region that is occupied by the PV1-nucleus. They formed a cloud around the axial cord of the parvalbumin-immunopositive cells, which they greatly outnumber (3:1). Only a small proportion of the neurons in the PV1-nucleus co-expressed both parvalbumin and Foxb1. In the light of these findings, a redesignation of this lateral hypothalamic structure as the PV1-Foxb1 nucleus would more accurately reflect its specific biochemical properties. |
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| Item Description: | Gesehen am 26.08.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1872-7972 |
| DOI: | 10.1016/j.neulet.2014.02.028 |