The impact of hematocrit on oxygenation-sensitive cardiovascular magnetic resonance

Oxygenation-sensitive (OS) Cardiovascular Magnetic Resonance (CMR) is a promising utility in the diagnosis of heart disease. Contrast in OS-CMR images is generated through deoxyhemoglobin in the tissue, which is negatively correlated with the signal intensity (SI). Thus, changing hematocrit levels m...

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Bibliographic Details
Main Authors: Günsch, Dominik (Author) , Nadeshalingam, Gobinath (Author) , Fischer, Kady (Author) , Stalder, Aurelien F. (Author) , Friedrich, Matthias (Author)
Format: Article (Journal)
Language:English
Published: 20 July 2016
In: Journal of cardiovascular magnetic resonance
Year: 2016, Volume: 18, Pages: 1-9
ISSN:1532-429X
DOI:10.1186/s12968-016-0262-1
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12968-016-0262-1
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Author Notes:Dominik P. Guensch, Gobinath Nadeshalingam, Kady Fischer, Aurelien F. Stalder and Matthias G. Friedrich
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Summary:Oxygenation-sensitive (OS) Cardiovascular Magnetic Resonance (CMR) is a promising utility in the diagnosis of heart disease. Contrast in OS-CMR images is generated through deoxyhemoglobin in the tissue, which is negatively correlated with the signal intensity (SI). Thus, changing hematocrit levels may be a confounder in the interpretation of OS-CMR results. We hypothesized that hemodilution confounds the observed signal intensity in OS-CMR images.
Item Description:Gesehen am 27.08.2020
Physical Description:Online Resource
ISSN:1532-429X
DOI:10.1186/s12968-016-0262-1