Gold-catalyzed intermolecular oxidative diyne cyclizations via 1,6-carbene transfer
A vinyl/α-oxo carbene is generated via an α-oxo carbene formation and subsequently transferred across the second alkyne. These highly active species can react with nitriles in an intermolecular fashion to provide substituted oxazoles. This methodology goes through 1,6-carbene shift and offers a rang...
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
2020
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| In: |
Advanced synthesis & catalysis
Year: 2019, Volume: 362, Issue: 4, Pages: 755-759 |
| ISSN: | 1615-4169 |
| DOI: | 10.1002/adsc.201901318 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1002/adsc.201901318 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/adsc.201901318 
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| Author Notes: | Qian Wang, Matthias Rudolph, Frank Rominger, and A. Stephen K. Hashmi |
| Summary: | A vinyl/α-oxo carbene is generated via an α-oxo carbene formation and subsequently transferred across the second alkyne. These highly active species can react with nitriles in an intermolecular fashion to provide substituted oxazoles. This methodology goes through 1,6-carbene shift and offers a range of valuable products. |
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| Item Description: | Version of record online: November 27, 2019 Gesehen am 02.09.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1615-4169 |
| DOI: | 10.1002/adsc.201901318 |