Ruthenium catalyzed direct asymmetric reductive amination of simple aliphatic ketones using ammonium iodide and hydrogen
On the direct asymmetric reductive amination of aliphatic ketones to primary amines: By using Ru‐Binaphane as catalyst and NH4I as the amine source, it is possible to aminate prochiral aliphatic ketones with moderate ee values up to 74 %.
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| Main Authors: | , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
10 June 2020
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| In: |
European journal of organic chemistry
Year: 2020, Issue: 30, Pages: 4796-4800 |
| ISSN: | 1099-0690 |
| DOI: | 10.1002/ejoc.202000750 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1002/ejoc.202000750 Verlag, lizenzpflichtig, Volltext: https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ejoc.202000750 
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| Author Notes: | Tamal Ghosh, Martin Ernst, A. Stephen K. Hashmi, and Thomas Schaub |
| Summary: | On the direct asymmetric reductive amination of aliphatic ketones to primary amines: By using Ru‐Binaphane as catalyst and NH4I as the amine source, it is possible to aminate prochiral aliphatic ketones with moderate ee values up to 74 %. |
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| Item Description: | Gesehen am 02.09.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1099-0690 |
| DOI: | 10.1002/ejoc.202000750 |