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Exploring MR regression patterns in rectal cancer during neoadjuvant radiochemotherapy with daily T2- and diffusion-weighted MRI

To date, only limited magnetic resonance imaging (MRI) data are available concerning tumor regression during neoadjuvant radiochemotherapy (RCT) of rectal cancer patients, which is a prerequisite for adaptive radiotherapy (RT) concepts. This exploratory study prospectively evaluated daily fractional...

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Main Authors: Bostel, Tilman (Author) , Dreher, Constantin (Author) , Wollschläger, Daniel (Author) , Mayer, A. (Author) , König, Franz (Author) , Bickelhaupt, Sebastian (Author) , Schlemmer, Heinz-Peter (Author) , Huber, Peter E. (Author) , Sterzing, Florian (Author) , Bäumer, Philipp (Author) , Debus, Jürgen (Author) , Nicolay, Nils (Author)
Format: Article (Journal)
Language:English
Published: 11 July 2020
In: Radiation oncology
Year: 2020, Volume: 15
ISSN:1748-717X
DOI:10.1186/s13014-020-01613-4
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s13014-020-01613-4
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Author Notes:T. Bostel, C. Dreher, D. Wollschläger, A. Mayer, F. König, S. Bickelhaupt, H.P. Schlemmer, P.E. Huber, F. Sterzing, P. Bäumer, J. Debus and N.H. Nicolay
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Summary:To date, only limited magnetic resonance imaging (MRI) data are available concerning tumor regression during neoadjuvant radiochemotherapy (RCT) of rectal cancer patients, which is a prerequisite for adaptive radiotherapy (RT) concepts. This exploratory study prospectively evaluated daily fractional MRI during neoadjuvant treatment to analyze the predictive value of MR biomarkers for treatment response.
Item Description:Gesehen am 03.09.2020
Physical Description:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-020-01613-4

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