Clinically actionable strategies for studying neural influences in cancer
Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the stra...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
11 June 2020
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| In: |
Cancer cell
Year: 2020, Volume: 38, Issue: 1, Pages: 11-14 |
| ISSN: | 1878-3686 |
| DOI: | 10.1016/j.ccell.2020.05.023 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ccell.2020.05.023 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S1535610820302737 |
| Author Notes: | Ihsan Ekin Demir, Carmen Mota Reyes, Wasfi Alrawashdeh, Güralp O. Ceyhan, Sylvie Deborde, Helmut Friess, Kivanc Görgülü, Rouzanna Istvanffy, David Jungwirth, Rohini Kuner, Maria Maryanovich, Shorook Na’ara, Simon Renders, Jami L. Saloman, Nicole N. Scheff, Hendrik Steenfadt, Pavel Stupakov, Vera Thiel, Divij Verma, Bengi Su Yilmaz, Ruth A. White, Timothy C. Wang, Richard J. Wong, Paul S. Frenette, Ziv Gil, and Brian M. Davis |
| Summary: | Neuro-glial activation is a recently identified hallmark of growing cancers. Targeting tumor hyperinnervation in preclinical and small clinical trials has yielded promising antitumor effects, highlighting the need of systematic analysis of neural influences in cancer (NIC). Here, we outline the strategies translating these findings from bench to the clinic. |
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| Item Description: | Gesehen am 08.09.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1878-3686 |
| DOI: | 10.1016/j.ccell.2020.05.023 |