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A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction

Takotsubo cardiomyopathy (TTC) remains a potentially life-threatening disease, which is clinically indistinguishable from acute myocardial infarction (MI). Today, no established biomarkers are available for the early diagnosis of TTC and differentiation from MI. MicroRNAs (miRNAs/miRs) emerge as pro...

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Main Authors: Jaguszewski, Milosz (Author) , Osipova, Julia (Author) , Ghadri, Jelena-Rima (Author) , Napp, Lars Christian (Author) , Widera, Christian (Author) , Franke, Jennifer (Author) , Fijalkowski, Marcin (Author) , Nowak, Radoslaw (Author) , Fijalkowska, Marta (Author) , Volkmann, Ingo (Author) , Katus, Hugo (Author) , Wollert, Kai C. (Author) , Bauersachs, Johann (Author) , Erne, Paul (Author) , Lüscher, Thomas F. (Author) , Thum, Thomas (Author) , Templin, Christian (Author)
Format: Article (Journal)
Language:English
Published: 2014
In: European heart journal
Year: 2013, Volume: 35, Issue: 15, Pages: 999-1006a
ISSN:1522-9645
DOI:10.1093/eurheartj/eht392
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1093/eurheartj/eht392
Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/eurheartj/article/35/15/999/645384
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Author Notes:Milosz Jaguszewski, Julia Osipova, Jelena-Rima Ghadri, Lars Christian Napp, Christian Widera, Jennifer Franke, Marcin Fijalkowski, Radoslaw Nowak, Marta Fijalkowska, Ingo Volkmann, Hugo A. Katus, Kai C. Wollert, Johann Bauersachs, Paul Erne, Thomas F. Lüscher, Thomas Thum, and Christian Templin
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Summary:Takotsubo cardiomyopathy (TTC) remains a potentially life-threatening disease, which is clinically indistinguishable from acute myocardial infarction (MI). Today, no established biomarkers are available for the early diagnosis of TTC and differentiation from MI. MicroRNAs (miRNAs/miRs) emerge as promising sensitive and specific biomarkers for cardiovascular disease. Thus, we sought to identify circulating miRNAs suitable for diagnosis of acute TTC and for distinguishing TTC from acute MI.
Item Description:Online publish-ahead-of-print 17 September 2013
Gesehen am 09.09.2020
Physical Description:Online Resource
ISSN:1522-9645
DOI:10.1093/eurheartj/eht392

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