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Assessment of aortic morphology and compliance in children and adolescents with Ullrich-Turner syndrome (UTS) using magnetic resonance imaging (MRI)

Aim: The aim of this study was to evaluate the morphology and elastic properties of the aorta in children and adolescents with Ullrich-Turner syndrome (UTS) treated with growth hormone, by using magnetic resonance imaging (MRI). Methods: Thirty-seven conscious UTS patients were examined using a 1.5-...

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Main Authors: Kneppo, Carolin (Author) , Eichhorn, Joachim (Author) , Ley, Sebastian (Author) , Schenk, Jens-Peter (Author) , Gorenflo, Matthias (Author) , Bettendorf, Markus (Author)
Format: Article (Journal)
Language:English
Published: 22.05.2014
In: The journal of pediatric endocrinology and metabolism
Year: 2014, Volume: 27, Issue: 9/10, Pages: 915-922
ISSN:2191-0251
DOI:10.1515/jpem-2013-0332
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1515/jpem-2013-0332
Verlag, lizenzpflichtig, Volltext: https://www.degruyterbrill.com/view/journals/jpem/27/9-10/article-p915.xml
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Author Notes:Carolin Kneppo, Joachim G. Eichhorn, Sebastian Ley, Jens P. Schenk, Matthias Gorenflo, Markus Bettendorf
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Summary:Aim: The aim of this study was to evaluate the morphology and elastic properties of the aorta in children and adolescents with Ullrich-Turner syndrome (UTS) treated with growth hormone, by using magnetic resonance imaging (MRI). Methods: Thirty-seven conscious UTS patients were examined using a 1.5-T whole-body MRI. Contrast-free three-dimensional (3D)-MR angiographies were performed, including 2D cine MRI, to calculate the aortic compliance (C) and cine of the aortic valve. Results: Changes of aortic morphology were evident in 40% of the patients, whereas six had more than one alteration. A bicuspid aortic valve was identified in three patients that were missed by previous echocardiography. The aortic compliances in UTS patients were similar to those in healthy persons. Conclusion: This study shows that aortic morphology and compliance can be assessed by MRI without using contrast agents and without sedation in children and adolescents with UTS.
Item Description:Gesehen am 10.09.2020
Physical Description:Online Resource
ISSN:2191-0251
DOI:10.1515/jpem-2013-0332

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