Corneal endothelial cell coating during phacoemulsification using a new dispersive hyaluronic acid ophthalmic viscosurgical device
Purpose - To compare the corneal endothelial coating of a new hyaluronic acid ophthalmic viscosurgical device (OVD) with dispersive properties with that of a standard hyaluronic acid OVD with cohesive properties. - Setting - David J. Apple International Laboratory for Ocular Pathology, Department of...
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
10 September 2014
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| In: |
Journal of cataract and refractive surgery
Year: 2014, Volume: 40, Issue: 11, Pages: 1879-1884 |
| ISSN: | 1873-4502 |
| DOI: | 10.1016/j.jcrs.2014.04.025 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jcrs.2014.04.025 Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0886335014011092 
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| Author Notes: | Florian T. A. Kretz, Il-Joo Limberger, Gerd U. Auffarth |
| Summary: | Purpose - To compare the corneal endothelial coating of a new hyaluronic acid ophthalmic viscosurgical device (OVD) with dispersive properties with that of a standard hyaluronic acid OVD with cohesive properties. - Setting - David J. Apple International Laboratory for Ocular Pathology, Department of Ophthalmology, University of Heidelberg, Germany. - Design - Experimental study. - Methods - The corneal endothelial cell coating of a new dispersive OVD (sodium hyaluronate 3% [Healon Endocoat]) and a standard cohesive hyaluronic acid OVD (sodium hyaluronate 1.4% [Healon GV]) as well as their combination using the soft-shell technique were evaluated. All OVDs were stained with fluorescein. Each of the 3 test groups comprised 10 porcine eyes. Cataract surgery was performed with identical phacoemulsification settings and time frames. Afterward, the cornea was trephined and a photograph taken of the endothelial side under blue light. The corneal coating with OVD was evaluated using planimetric image-analysis software. - Results - The least endothelial coating was in the cohesive group (71%), while the dispersive group had statistically significantly higher adherence to the endothelium (87%) (P=.0009). The greatest endothelial coating was in the soft-shell technique group (93%); however, the difference between that group and the dispersive group was not statistically significant (P=.0962). - Conclusion - The new dispersive hyaluronic acid OVD with a low molecular weight showed a greater adherence to the endothelial surface than the standard cohesive hyaluronic acid OVD with a higher molecular weight. - Financial Disclosure - No author has a financial or proprietary interest in any material or method mentioned. |
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| Item Description: | Gesehen am 22.09.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1873-4502 |
| DOI: | 10.1016/j.jcrs.2014.04.025 |