Using immunotherapy to boost the abscopal effect

The abscopal effect, which is the regression of metastatic cancer at distant sites during radiotherapy, is somewhat rare but can be promoted by immunotherapy. This Opinion article describes emerging concepts and limitations of using a combination of radiotherapy and immunotherapy to boost the abscop...

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Bibliographic Details
Main Authors: Ngwa, Wilfred (Author) , Hesser, Jürgen (Author)
Format: Article (Journal)
Language:English
Published: May 2018
In: Nature reviews. Cancer
Year: 2018, Volume: 18, Issue: 5, Pages: 313-322
ISSN:1474-1768
DOI:10.1038/nrc.2018.6
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nrc.2018.6
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nrc.2018.6
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Author Notes:Wilfred Ngwa, Omoruyi Credit Irabor, Jonathan D. Schoenfeld, Jürgen Hesser, Sandra Demaria and Silvia C. Formenti
Description
Summary:The abscopal effect, which is the regression of metastatic cancer at distant sites during radiotherapy, is somewhat rare but can be promoted by immunotherapy. This Opinion article describes emerging concepts and limitations of using a combination of radiotherapy and immunotherapy to boost the abscopal effect.
Item Description:Gesehen am 29.09.2020
Physical Description:Online Resource
ISSN:1474-1768
DOI:10.1038/nrc.2018.6