Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma
Drug-induced multidrug resistance (MDR) has been linked to overexpression of drug transporting proteins in head and neck squamous cell carcinoma (HNSCC) in vitro. The aim of this work was to reassess these findings in a murine xenograft model.
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| Main Authors: | , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
21 Jan 2014
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| In: |
Cancer biology & therapy
Year: 2014, Volume: 15, Issue: 4, Pages: 436-442 |
| ISSN: | 1555-8576 |
| DOI: | 10.4161/cbt.27632 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.4161/cbt.27632 Verlag, lizenzpflichtig, Volltext: https://www.tandfonline.com/doi/full/10.4161/cbt.27632 |
| Author Notes: | Dirk Theile, Zoltan Gal, Rolf Warta, Juan Pablo Rigalli, Bernd Lahrmann, Niels Grabe, Christel Herold-Mende, Gerhard Dyckhoff & Johanna Weiss |
| Summary: | Drug-induced multidrug resistance (MDR) has been linked to overexpression of drug transporting proteins in head and neck squamous cell carcinoma (HNSCC) in vitro. The aim of this work was to reassess these findings in a murine xenograft model. |
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| Item Description: | Gesehen am 29.09.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1555-8576 |
| DOI: | 10.4161/cbt.27632 |