Antiproliferative efficacies but minor drug transporter inducing effects of paclitaxel, cisplatin, or 5-fluorouracil in a murine xenograft model for head and neck squamous cell carcinoma

Drug-induced multidrug resistance (MDR) has been linked to overexpression of drug transporting proteins in head and neck squamous cell carcinoma (HNSCC) in vitro. The aim of this work was to reassess these findings in a murine xenograft model.

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Main Authors: Theile, Dirk (Author) , Gál, Zoltán (Author) , Warta, Rolf (Author) , Rigalli, Juan Pablo (Author) , Lahrmann, Bernd (Author) , Grabe, Niels (Author) , Herold-Mende, Christel (Author) , Dyckhoff, Gerhard (Author) , Weiß, Johanna (Author)
Format: Article (Journal)
Language:English
Published: 21 Jan 2014
In: Cancer biology & therapy
Year: 2014, Volume: 15, Issue: 4, Pages: 436-442
ISSN:1555-8576
DOI:10.4161/cbt.27632
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.4161/cbt.27632
Verlag, lizenzpflichtig, Volltext: https://www.tandfonline.com/doi/full/10.4161/cbt.27632
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Author Notes:Dirk Theile, Zoltan Gal, Rolf Warta, Juan Pablo Rigalli, Bernd Lahrmann, Niels Grabe, Christel Herold-Mende, Gerhard Dyckhoff & Johanna Weiss
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Summary:Drug-induced multidrug resistance (MDR) has been linked to overexpression of drug transporting proteins in head and neck squamous cell carcinoma (HNSCC) in vitro. The aim of this work was to reassess these findings in a murine xenograft model.
Item Description:Gesehen am 29.09.2020
Physical Description:Online Resource
ISSN:1555-8576
DOI:10.4161/cbt.27632