Influence of St. John’s wort on the steadystate pharmacokinetics and metabolism of bosentan

We assessed the effect of St. John’s wort (SJW) on bosentan pharmacokinetics at steady-state in different CYP2C9 genotypes in healthy volunteers.

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Bibliographic Details
Main Authors:	Markert, Christoph (Author) , Ngui, Prisca (Author) , Hellwig, Regina (Author) , Wirsching, Theresia (Author) , Kastner, Ida Maria (Author) , Riedel, Klaus-Dieter (Author) , Burhenne, Jürgen (Author) , Weiß, Johanna (Author) , Mikus, Gerd (Author) , Haefeli, Walter E. (Author)
Format:	Article (Journal)
Language:	English
Published:	2014
In:	International journal of clinical pharmacology and therapeutics Year: 2014, Volume: 52, Issue: 04, Pages: 328-336
DOI:	10.5414/CP202048
Online Access:	Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.5414/CP202048 Verlag, lizenzpflichtig, Volltext: http://www.dustri.com/article_response_page.html?artId=11217&doi=10.5414/CP202048&L=0
Author Notes:	Christoph Markert, Prisca Ngui, Regina Hellwig, Theresia Wirsching, Ida Maria Kastner, Klaus-Dieter Riedel, Jürgen Burhenne, Johanna Weiss, Gerd Mikus, Walter E. Haefeli

Description
Summary:	We assessed the effect of St. John’s wort (SJW) on bosentan pharmacokinetics at steady-state in different CYP2C9 genotypes in healthy volunteers.
Item Description:	Gesehen am 30.09.2020
Physical Description:	Online Resource
DOI:	10.5414/CP202048