FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium
Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified FGFR2 as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF) receptors might also modify risk. We tested this hypothesis by studying genotyped sing...
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| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
18 February 2014
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| In: |
British journal of cancer
Year: 2014, Volume: 110, Issue: 4, Pages: 1088-1100 |
| ISSN: | 1532-1827 |
| DOI: | 10.1038/bjc.2013.769 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/bjc.2013.769 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/bjc2013769 
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| Author Notes: | D. Agarwal, S. Pineda, K. Michailidou, J. Herranz, G. Pita, L.T. Moreno, M.R. Alonso, J. Dennis, Q. Wang, M.K. Bolla, K.B. Meyer, P. Menéndez-Rodríguez, D. Hardisson, M. Mendiola, A. González-Neira, A. Lindblom, S. Margolin, A. Swerdlow, A. Ashworth, N. Orr, M. Jones, K. Matsuo, H. Ito, H. Iwata, N. Kondo, M. Hartman, M. Hui, W.Y. Lim, P.T.-C. Iau, E. Sawyer, I. Tomlinson, M. Kerin, N. Miller, D. Kang, J.-Y. Choi, S.K. Park, D.-Y. Noh, J.L. Hopper, D.F. Schmidt, E. Makalic, M.C. Southey, S.H. Teo, C.H. Yip, K. Sivanandan, W.-T. Tay, H. Brauch, T. Brüning, U. Hamann, A.M. Dunning, M. Shah, I.L. Andrulis, J.A. Knight, G. Glendon, S. Tchatchou, M.K. Schmidt, A. Broeks, E.H. Rosenberg, L. J. van't Veer, P.A. Fasching, S.P. Renner, A.B. Ekici, M.W. Beckmann, C.-Y. Shen, C.-N. Hsiung, J.-C. Yu, M.-F. Hou, W. Blot, Q. Cai, A.H. Wu, C.-C. Tseng, D. Van Den Berg, D.O. Stram, A. Cox, I.W. Brock, M.W.R. Reed, K. Muir, A. Lophatananon, S. Stewart-Brown, P. Siriwanarangsan, W. Zheng, S. Deming-Halverson, M.J. Shrubsole, J. Long, X.-O. Shu, W. Lu, Y.-T. Gao, B. Zhang, P. Radice, P. Peterlongo, S. Manoukian, F. Mariette, S. Sangrajrang, J. McKay, F.J. Couch, A.E. Toland, D. Yannoukakos, O. Fletcher, N. Johnson, I. dos Santos Silva, J. Peto, F. Marme, B. Burwinkel, P. Guénel, T. Truong, M. Sanchez, C. Mulot, S.E. Bojesen, B.G. Nordestgaard, H. Flyer, H. Brenner, A.K. Dieffenbach, V. Arndt, C. Stegmaier, A. Mannermaa, V. Kataja, V.-M. Kosma, J.M. Hartikainen, D. Lambrechts, B.T. Yesilyurt, G. Floris, K. Leunen, J. Chang-Claude, A. Rudolph, P. Seibold, D. Flesch-Janys, X. Wang, J.E. Olson, C. Vachon, K. Purrington, G.G. Giles, G. Severi, L. Baglietto, C.A. Haiman, B.E. Henderson, F. Schumacher, L. Le Marchand, J. Simard, M. Dumont, M. S. Goldberg, F. Labrèche, R. Winqvist, K. Pylkäs, A. Jukkola-Vuorinen, M. Grip, P. Devilee, R.a.E.M. Tollenaar, C. Seynaeve, M. García-Closas, S.J. Chanock, J. Lissowska, J.D. Figueroa, K. Czene, M. Eriksson, K. Humphreys, H. Darabi, M.J. Hooning, M. Kriege, J.M. Collée, M. Tilanus-Linthorst, J. Li, A. Jakubowska, J. Lubinski, K. Jaworska-Bieniek, K. Durda, H. Nevanlinna, T.A. Muranen, K. Aittomäki, C. Blomqvist, N. Bogdanova, T. Dörk, P. Hall, G. Chenevix-Trench, D.F. Easton, P.D.P. Pharoah, J.I. Arias-Perez, P. Zamora, J. Benítez, and R.L. Milne |
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| 520 | |a Breast cancer is one of the most common malignancies in women. Genome-wide association studies have identified FGFR2 as a breast cancer susceptibility gene. Common variation in other fibroblast growth factor (FGF) receptors might also modify risk. We tested this hypothesis by studying genotyped single-nucleotide polymorphisms (SNPs) and imputed SNPs in FGFR1, FGFR3, FGFR4 and FGFRL1 in the Breast Cancer Association Consortium. | ||
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