Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs

G-protein-coupled receptors (GPCRs), in the form of monomers or homodimers that bind heterotrimeric G proteins, are fundamental in the transfer of extracellular stimuli to intracellular signaling pathways. Different GPCRs may also interact to form heteromers that are novel signaling units. Despite t...

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Bibliographic Details

Main Authors:	Navarro, Gemma (Author) , Cordomí, Arnau (Author) , Zelman-Femiak, Monika (Author) , Brugarolas, Marc (Author) , Moreno, Estefania (Author) , Aguinaga, David (Author) , Perez-Benito, Laura (Author) , Cortés, Antoni (Author) , Casadó, Vicent (Author) , Mallol, Josefa (Author) , Canela, Enric I. (Author) , Lluís, Carme (Author) , Pardo, Leonardo (Author) , García-Sáez, Ana J. (Author) , McCormick, Peter J. (Author) , Franco, Rafael (Author)
Format:	Article (Journal)
Language:	English
Published:	05 April 2016
In:	BMC biology Year: 2016, Volume: 14
ISSN:	1741-7007
DOI:	10.1186/s12915-016-0247-4
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12915-016-0247-4
Author Notes:	Gemma Navarro, Arnau Cordomí, Monika Zelman-Femiak, Marc Brugarolas, Estefania Moreno, David Aguinaga, Laura Perez-Benito, Antoni Cortés, Vicent Casadó, Josefa Mallol, Enric I. Canela, Carme Lluís, Leonardo Pardo, Ana J. García-Sáez, Peter J. McCormick and Rafael Franco