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Specificity of abnormal brain volume in major depressive disorder: a comparison with borderline personality disorder

Abnormal brain volume has been frequently demonstrated in major depressive disorder (MDD). It is unclear if these findings are specific for MDD since aberrant brain structure is also present in disorders with depressive comorbidity and affective dysregulation, such as borderline personality disorder...

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Bibliographic Details
Main Authors: Depping, Malte S. (Author) , Wolf, Nadine D. (Author) , Vasic, Nenad (Author) , Sambataro, Fabio (Author) , Thomann, Philipp (Author) , Wolf, Robert Christian (Author)
Format: Article (Journal)
Language:English
Published: 2015
In: Journal of affective disorders
Year: 2015, Volume: 174, Pages: 650-657
ISSN:1573-2517
DOI:10.1016/j.jad.2014.11.059
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jad.2014.11.059
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0165032714007836
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Author Notes:Malte S. Depping, Nadine D. Wolf, Nenad Vasic, Fabio Sambataro, Philipp A. Thomann, R. Christian Wolf
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Summary:Abnormal brain volume has been frequently demonstrated in major depressive disorder (MDD). It is unclear if these findings are specific for MDD since aberrant brain structure is also present in disorders with depressive comorbidity and affective dysregulation, such as borderline personality disorder (BPD). In this transdiagnostic study, we aimed to investigate if regional brain volume loss differentiates between MDD and BPD. Further, we tested for associations between brain volume and clinical variables within and between diagnostic groups.
Item Description:Available online 9 December 2014
Gesehen am 13.10.2020
Physical Description:Online Resource
ISSN:1573-2517
DOI:10.1016/j.jad.2014.11.059

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