Practical investigation of the performance of robust logistic regression to predict the genetic risk of hypertension
Logistic regression is usually applied to investigate the association between inherited genetic variants and a binary disease phenotype. A limitation of standard methods used to estimate the parameters of logistic regression models is their strong dependence on a few observations deviating from the...
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| Main Authors: | , , , , , , |
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| Format: | Article (Journal) Conference Paper |
| Language: | English |
| Published: |
17 June 2014
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| In: |
BMC proceedings
Year: 2014, Volume: 8 |
| ISSN: | 1753-6561 |
| DOI: | 10.1186/1753-6561-8-S1-S65 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1186/1753-6561-8-S1-S65 Verlag, lizenzpflichtig, Volltext: https://bmcproc.biomedcentral.com/articles/10.1186/1753-6561-8-S1-S65 |
| Author Notes: | Miriam Kesselmeier, Carine Legrand, Barbara Peil, Maria Kabisch, Christine Fischer, Ute Hamann, Justo Lorenzo Bermejo |
| Summary: | Logistic regression is usually applied to investigate the association between inherited genetic variants and a binary disease phenotype. A limitation of standard methods used to estimate the parameters of logistic regression models is their strong dependence on a few observations deviating from the majority of the data. |
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| Item Description: | Gesehen am 14.10.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1753-6561 |
| DOI: | 10.1186/1753-6561-8-S1-S65 |