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System and path planning algorithm for low-kV X-ray free-form surface irradiation

Objective: Intraoperative radiotherapy (IORT) after surgical resection using a low-kV-X-ray source is a proven method used in cancer treatment. However, the shape and size of the targeted surface area are limited to the size of the available applicators. This can lead to nonconformal and therefore s...

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Bibliographic Details
Main Authors: Rothfuß, Andreas (Author) , Bürgy, Daniel (Author) , Schneider, Frank (Author) , Wenz, Frederik (Author) , Clausen, Sven (Author)
Format: Article (Journal)
Language:English
Published: 27 February 2018
In: The international journal of medical robotics and computer assisted surgery
Year: 2018, Volume: 14, Issue: 3
ISSN:1478-596X
DOI:10.1002/rcs.1899
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/rcs.1899
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/rcs.1899
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Author Notes:Andreas Rothfuss, Oliver Oesterle, Daniel Bürgy, Charles Nwankwo, Frank Schneider, Auguste van Poelgeest, Frederik Wenz, Jan Stallkamp, Sven Clausen
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Summary:Objective: Intraoperative radiotherapy (IORT) after surgical resection using a low-kV-X-ray source is a proven method used in cancer treatment. However, the shape and size of the targeted surface area are limited to the size of the available applicators. This can lead to nonconformal and therefore suboptimal treatment for many patients. Methods: A system is proposed comprising an X-ray source with an applicator for surface irradiation mounted on a robotic arm. This is controlled by an algorithm designed for planning the required continuous path, enabling irradiation of any desired shape with a controlled dose distribution. Results: The system is shown to be capable of irradiating areas composed of rectangles on a flat surface with a homogeneity index of less than 7% inside the targeted area. Conclusion: The presented results demonstrate the potential of the proposed setup to eliminate the current limitations, leading to better treatment of patients.
Item Description:Gesehen am 15.10.2020
Physical Description:Online Resource
ISSN:1478-596X
DOI:10.1002/rcs.1899

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