An efficient approach to the synthesis of hydrazinyl pseudo-peptides
New hydrazinyl pseudo-peptides have been obtained from Ugi four-component reaction (4CR). The 5-hydrazinyl-5-oxopentanoic acids used as starting materials were prepared by the reaction of hydrazides with anhydrides. Mild reaction conditions, high atom economy, bond-forming efficiency, and easy worku...
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| Main Authors: | , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
10 December 2014
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| In: |
Helvetica chimica acta
Year: 2014, Volume: 97, Issue: 12, Pages: 1630-1637 |
| ISSN: | 1522-2675 |
| DOI: | 10.1002/hlca.201400061 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/hlca.201400061 Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/hlca.201400061 |
| Author Notes: | Vaezeh Fathi, Sorour Ramezanpour, Saeed Balalaie, Frank Rominger, and Hamid Reza Bijanzadeh |
| Summary: | New hydrazinyl pseudo-peptides have been obtained from Ugi four-component reaction (4CR). The 5-hydrazinyl-5-oxopentanoic acids used as starting materials were prepared by the reaction of hydrazides with anhydrides. Mild reaction conditions, high atom economy, bond-forming efficiency, and easy workup are advantages of this approach. The products have four amide bonds and high potential for H-bonding. |
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| Item Description: | Gesehen am 16.10.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1522-2675 |
| DOI: | 10.1002/hlca.201400061 |