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Itching in patients with chronic hand eczema: data from the CARPE registry

Background: Itching is a leading symptom of chronic hand eczema (CHE) having a great impact on patients. The determinants of itching in CHE are unclear. Objective: We performed a cross-sectional analysis investigating factors associated with the presence and severity of itch in CHE patients from the...

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Main Authors: Ruppert, Linda M. (Author) , Apfelbacher, Christian (Author) , Molin, Sonja (Author) , Bauer, Andrea (Author) , Mahler, Vera (Author) , Schmitt, Jochen (Author) , Elsner, Peter (Author) , Diepgen, Thomas L. (Author) , Weisshaar, Elke (Author)
Format: Article (Journal)
Language:English
Published: August 16, 2014
In: Dermatology
Year: 2014, Volume: 229, Issue: 2, Pages: 146-153
ISSN:1421-9832
DOI:10.1159/000362901
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000362901
Verlag, lizenzpflichtig, Volltext: https://www.karger.com/Article/FullText/362901
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Author Notes:Linda Ruppert, Christian Apfelbacher, Sonja Molin, Andrea Bauer, Vera Mahler, Jochen Schmitt, Peter Elsner, Thomas L. Diepgen, Elke Weisshaar
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Summary:Background: Itching is a leading symptom of chronic hand eczema (CHE) having a great impact on patients. The determinants of itching in CHE are unclear. Objective: We performed a cross-sectional analysis investigating factors associated with the presence and severity of itch in CHE patients from the CARPE registry. Methods: We present baseline data on itch in relationship with sociodemographic factors, severity of CHE, atopy, contact allergy, treatment and patient- reported outcomes including health-related quality of life (HRQoL). Results: Of 1,051 patients with CHE, 78.1% reported itching. Significant positive associations with itching were observed for younger age groups (17-25 and 26-45 years), for moderate, severe and very severe CHE and for small/moderate impairment in HRQoL. Atopic skin diathesis, hardly being able to realize treatment recommendations and very or extremely large impairments in HRQoL were associated with itch severity. Conclusion: Taking the identified variables into account may help identify vulnerable groups most affected by (severe) itch.
Item Description:Gesehen am 20.10.2020
Physical Description:Online Resource
ISSN:1421-9832
DOI:10.1159/000362901

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