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Duration of SARS-CoV-2 RNA detection in COVID-19 patients in home isolation, Rhineland-Palatinate, Germany, 2020: an interval-censored survival analysis

We analysed consecutive RT-qPCR results of 537 symptomatic coronavirus disease (COVID-19) patients in home quarantine. Respectively 2, 3, and 4 weeks after symptom onset, 50%, 25% and 10% of patients had detectable RNA from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). In patients wi...

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Main Authors: Omar, Sarah (Author) , Bartz, Christoph (Author) , Becker, Sabine (Author) , Basenach, Silke (Author) , Pfeifer, Sandra (Author) , Trapp, Corinna (Author) , Hamm, Hildegard (Author) , Schlichting, Hans Christoph (Author) , Friederichs, Magdalena (Author) , Koch, Ulrich (Author) , Jestrabek, Christian (Author) , Hilger, Ernst (Author) , Vogt, Manfred (Author) , Jahn, Klaus (Author) , Chen, Simiao (Author) , Bärnighausen, Till (Author) , Zanger, Philipp (Author)
Format: Article (Journal)
Language:English
Published: 30 July 2020
In: Eurosurveillance
Year: 2020, Volume: 25, Issue: 30
ISSN:1560-7917
DOI:10.2807/1560-7917.ES.2020.25.30.2001292
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.2807/1560-7917.ES.2020.25.30.2001292
Verlag, lizenzpflichtig, Volltext: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.30.2001292
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Author Notes:Sarah Omar, Christoph Bartz, Sabine Becker, Silke Basenach, Sandra Pfeifer, Corinna Trapp, Hildegard Hamm, Hans Christoph Schlichting, Magdalena Friederichs, Ulrich Koch, Christian Jestrabek, Ernst Hilger, Manfred Vogt, Klaus Jahn, Simiao Chen, Till Bärnighausen, Philipp Zanger, on behalf of the Palatina Public Health Study Group
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Summary:We analysed consecutive RT-qPCR results of 537 symptomatic coronavirus disease (COVID-19) patients in home quarantine. Respectively 2, 3, and 4 weeks after symptom onset, 50%, 25% and 10% of patients had detectable RNA from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). In patients with mild COVID-19, RNA detection is likely to outlast currently known periods of infectiousness by far and fixed time periods seem more appropriate in determining the length of home isolation than laboratory-based approaches.
Item Description:Gesehen am 26.10.2020
Physical Description:Online Resource
ISSN:1560-7917
DOI:10.2807/1560-7917.ES.2020.25.30.2001292

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