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Computer-assisted cognitive remediation in schizophrenia: efficacy of an individualizedvs. generic exercise plan

Computer-assisted cognitive remediation (CACR) is an economical, adjustable, and effective treatment for individuals with schizophrenia. The current randomized controlled study examined whether an individualized or generic exercise plan in CACR is superior in patients with multiple cognitive deficit...

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Main Authors: Bossert, Magdalena (Author) , Westermann, Celina (Author) , Schilling, Thomas M. (Author) , Weisbrod, Matthias (Author) , Roesch-Ely, Daniela (Author) , Aschenbrenner, Steffen (Author)
Format: Article (Journal)
Language:English
Published: 16 September 2020
In: Frontiers in psychiatry
Year: 2020, Volume: 11
ISSN:1664-0640
DOI:10.3389/fpsyt.2020.555052
Online Access:Resolving-System, Volltext: http://doi.org/10.3389/fpsyt.2020.555052
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Author Notes:Magdalena Bossert, Celina Westermann, Thomas M. Schilling, Matthias Weisbrod, Daniela Roesch-Ely and Steffen Aschenbrenner
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Summary:Computer-assisted cognitive remediation (CACR) is an economical, adjustable, and effective treatment for individuals with schizophrenia. The current randomized controlled study examined whether an individualized or generic exercise plan in CACR is superior in patients with multiple cognitive deficits compared to treatment-as-usual (TAU). Fifty-nine inpatients diagnosed with schizophrenia were randomly assigned to 1) TAU, 2) TAU plus an individualized exercise plan in CACR, or 3) TAU plus a generic exercise plan in CACR. Neuropsychological performance, psychopathology, and functional outcome were assessed at baseline and post-treatment. The results show a medium to large training effect for all neuropsychological performance measures. Contrary to our expectations the neuropsychological improvement over time did not differ between groups. Self-reported depression, global level of functioning, and activity and participation functioning showed a significant improvement from baseline to post-treatment. However no further group, time, or interaction effects for other psychopathology and functional outcome could be demonstrated. Possible implications for clinical use of CACR and future studies are discussed.
Item Description:Gesehen am 09.11.2020
Physical Description:Online Resource
ISSN:1664-0640
DOI:10.3389/fpsyt.2020.555052

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