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Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose: aktueller Stand und Empfehlungen in Deutschland = Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : current status and recommendations in Germany

After years of low incidence, a large increase of new tuberculosis (TB) cases has been reported in Germany since 2015. New immunotherapies for the treatment of multiple sclerosis (MS) are associated with a reduced immune competence and a potential increased risk for infections. Most neurologists lac...

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Main Authors: Bittner, Stefan (Author) , Engel, Sinah (Author) , Lange, Christoph (Author) , Weber, Martin S. (Author) , Haghikia, Aiden (Author) , Luessi, Felix (Author) , Korn, Thomas (Author) , Klotz, Luisa (Author) , Bayas, Antonios (Author) , Paul, Friedemann (Author) , Heesen, Christoph (Author) , Stangel, Martin (Author) , Wildemann, Brigitte (Author) , Bergh, Florian Then (Author) , Tackenberg, Björn (Author) , Trebst, Corinna (Author) , Warnke, Clemens (Author) , Linker, Ralf (Author) , Kerschensteiner, Martin (Author) , Zettl, Uwe (Author) , Tumani, Hayrettin (Author) , Brück, Wolfgang (Author) , Meuth, Sven G. (Author) , Kümpfel, Tanja (Author) , Hemmer, Bernhard (Author) , Wiendl, Heinz (Author) , Gold, Ralf (Author) , Zipp, Frauke (Author)
Format: Article (Journal)
Language:German
Published: 11. Juli 2019
In: Der Nervenarzt
Year: 2019, Volume: 90, Issue: 12, Pages: 1245-1253
ISSN:1433-0407
DOI:10.1007/s00115-019-0760-0
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00115-019-0760-0
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Author Notes:Stefan Bittner, Sinah Engel, Christoph Lange, Martin S. Weber, Aiden Haghikia, Felix Luessi, Thomas Korn, Luisa Klotz, Antonios Bayas, Friedemann Paul, Christoph Heesen, Martin Stangel, Brigitte Wildemann, Florian Then Bergh, Björn Tackenberg, Corinna Trebst, Clemens Warnke, Ralf Linker, Martin Kerschensteiner, Uwe Zettl, Hayrettin Tumani, Wolfgang Brück, Sven G. Meuth, Tanja Kümpfel, Bernhard Hemmer, Heinz Wiendl, Ralf Gold, Frauke Zipp
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Summary:After years of low incidence, a large increase of new tuberculosis (TB) cases has been reported in Germany since 2015. New immunotherapies for the treatment of multiple sclerosis (MS) are associated with a reduced immune competence and a potential increased risk for infections. Most neurologists lack specific experiences with TB infections. This article summarizes specific recommendations for the diagnostics and treatment of TB under MS immunotherapies with a focus on the situation in Germany. Due to low case numbers and little experience with the risk of TB under the new immunotherapies, the clinical competence network for MS (KKNMS) consensus recommendations have a low grade of evidence.
Item Description:Gesehen am 16.11.2020
Physical Description:Online Resource
ISSN:1433-0407
DOI:10.1007/s00115-019-0760-0

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