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Overcoming immunosuppression as a new immunotherapeutic approach against pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of malignancy. Via a broad stimulation of the immune system, PDAC activates both antitumor immune responses and immunosuppressive mechanisms. We propose that new immunotherapeutic strategies for the management of PDAC should be de...

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Bibliographic Details
Main Authors: Bazhin, Alexandr V. (Author) , Bayry, Jagadeesh (Author) , Umansky, Viktor (Author) , Werner, Jens (Author) , Karakhanova, Svetlana (Author)
Format: Article (Journal)
Language:English
Published: 23 Jul 2013
In: OncoImmunology
Year: 2013, Volume: 2, Issue: 9
ISSN:2162-402X
DOI:10.4161/onci.25736
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.4161/onci.25736
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Author Notes:Alexandr V Bazhin, Jagadeesh Bayry, Viktor Umansky, Jens Werner, and Svetlana Karakhanova
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Summary:Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of malignancy. Via a broad stimulation of the immune system, PDAC activates both antitumor immune responses and immunosuppressive mechanisms. We propose that new immunotherapeutic strategies for the management of PDAC should be designed to specifically neutralize the immunosuppressive tumor microenvironment.
Item Description:Gesehen am 16.11.2020
Physical Description:Online Resource
ISSN:2162-402X
DOI:10.4161/onci.25736

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