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Overcoming immunosuppression as a new immunotherapeutic approach against pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of malignancy. Via a broad stimulation of the immune system, PDAC activates both antitumor immune responses and immunosuppressive mechanisms. We propose that new immunotherapeutic strategies for the management of PDAC should be de...

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Hauptverfasser: Bazhin, Alexandr V. (VerfasserIn) , Bayry, Jagadeesh (VerfasserIn) , Umansky, Viktor (VerfasserIn) , Werner, Jens (VerfasserIn) , Karakhanova, Svetlana (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 23 Jul 2013
In: OncoImmunology
Year: 2013, Jahrgang: 2, Heft: 9
ISSN:2162-402X
DOI:10.4161/onci.25736
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.4161/onci.25736
Volltext
Verfasserangaben:Alexandr V Bazhin, Jagadeesh Bayry, Viktor Umansky, Jens Werner, and Svetlana Karakhanova
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Zusammenfassung:Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of malignancy. Via a broad stimulation of the immune system, PDAC activates both antitumor immune responses and immunosuppressive mechanisms. We propose that new immunotherapeutic strategies for the management of PDAC should be designed to specifically neutralize the immunosuppressive tumor microenvironment.
Beschreibung:Gesehen am 16.11.2020
Beschreibung:Online Resource
ISSN:2162-402X
DOI:10.4161/onci.25736

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