Atypical frontal brain activation in ADHD: preschool and elementary school boys and girls

Objective - To investigate patterns of frontal brain activation in unmedicated preschool and school boys and girls with attention-deficit/hyperactivity disorder (ADHD). - Method - Baseline electroencephalographic activity of 117 children (66 aged 4 years. 51 aged 8 years) was subjected to power spec...

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Hauptverfasser: Baving, Lioba (VerfasserIn) , Laucht, Manfred (VerfasserIn) , Schmidt, Martin H. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 1999
In: Journal of the American Academy of Child and Adolescent Psychiatry
Year: 2010, Jahrgang: 38, Heft: 11, Pages: 1363-1371
ISSN:1527-5418
DOI:10.1097/00004583-199911000-00010
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1097/00004583-199911000-00010
Verlag, lizenzpflichtig, Volltext: http://www.sciencedirect.com/science/article/pii/S0890856709666855
Volltext
Verfasserangaben:Lioba Baving, Manfred Laucht, Martin H. Schmidt
Beschreibung
Zusammenfassung:Objective - To investigate patterns of frontal brain activation in unmedicated preschool and school boys and girls with attention-deficit/hyperactivity disorder (ADHD). - Method - Baseline electroencephalographic activity of 117 children (66 aged 4 years. 51 aged 8 years) was subjected to power spectral analysis, and laterality scores were determined. - Results - Boys with ADHD exhibited a less right-lateralized frontal activation pattern than normal-control boys. Girls with ADHD displayed a more right-lateralized frontal activation pattern than normal control girls. This finding applied to children at both 41/2 and 8 years of age. There was no difference between children with ADHD and children with ADHD plus oppositional defiant disorder. - Conclusions - This pattern of frontal brain activation is in line with magnetic resonance imaging studies of ADHD. It could be demonstrated in children as young as 41/2 years, as well as in school-age children. The opposite direction of asymmetry in boys and girls stresses the importance of gender-specific analyses in ADHD.
Beschreibung:Online 4 January 2010
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Beschreibung:Online Resource
ISSN:1527-5418
DOI:10.1097/00004583-199911000-00010