Topical treatment of tinea pedis using 6 % coriander oil in unguentum leniens: a randomized, controlled, comparative pilot study
<b><i>Background:</i></b> The antifungal activity of coriander oil has already been demonstrated in vitro. <b><i>Objective:</i></b> Evaluation of the efficacy and tolerability of 6% coriander oil in unguentum leniens in the treatment of interdigital ti...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
March 1, 2013
|
| In: |
Dermatology
Year: 2013, Volume: 226, Issue: 1, Pages: 47-51 |
| ISSN: | 1421-9832 |
| DOI: | 10.1159/000346641 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1159/000346641 Verlag, lizenzpflichtig, Volltext: https://www.karger.com/Article/FullText/346641 
|
| Author Notes: | F.C. Beikert, Z. Anastasiadou, B. Fritzen, U. Frank, M. Augustin |
| Summary: | <b><i>Background:</i></b> The antifungal activity of coriander oil has already been demonstrated in vitro. <b><i>Objective:</i></b> Evaluation of the efficacy and tolerability of 6% coriander oil in unguentum leniens in the treatment of interdigital tinea pedis. <b><i>Methods:</i></b> Half-side comparative pilot study on subjects with symmetric, bilateral interdigital tinea pedis. Active drug and placebo control were applied twice daily on the affected areas, and follow-up visits were performed on days 14 and 28. <b><i>Results:</i></b> 40 participants (mean age 52.5 years, 60% male) were included in the study. For 6% coriander oil in unguentum leniens, a highly significant improvement of the clinical signs (p < 0.0001) was observed during the entire observation period; the number of positive fungal cultures also tended to decrease (p = 0.0654). The tolerability of the tested substances was good. <b><i>Conclusion:</i></b> Coriander oil is effective and well tolerated in the treatment of interdigital tinea pedis. |
|---|---|
| Item Description: | Gesehen am 19.11.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1421-9832 |
| DOI: | 10.1159/000346641 |