Synthetic estrogens-mediated activation of JNK intracellular signaling molecule
Signal transduction pathways regulate the transmission of specific signals to the cells from the surface to the nucleus. Activation of protein kinases such as JNKs (c-jun amino-terminal kinase), a subgroup of the mitogen activated protein kinase (MAPK) family, results in regulation of important cell...
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| Autori principali: | , , , |
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| Natura: | Article (Journal) |
| Lingua: | inglese |
| Pubblicazione: |
2009
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| In: |
Gynecological endocrinology
Year: 2001, Volume: 15, Fascicolo: 2, Pages: 135-141 |
| ISSN: | 1473-0766 |
| DOI: | 10.1080/gye.15.2.135.141 |
| Accesso online: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1080/gye.15.2.135.141 Verlag, lizenzpflichtig, Volltext: https://www.tandfonline.com/doi/abs/10.1080/gye.15.2.135.141 
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| Note sull'autore: | S. Prifti, P. Mall, T. Strowitzki and T. Rabe |
| Riassunto: | Signal transduction pathways regulate the transmission of specific signals to the cells from the surface to the nucleus. Activation of protein kinases such as JNKs (c-jun amino-terminal kinase), a subgroup of the mitogen activated protein kinase (MAPK) family, results in regulation of important cellular functions like cell growth and differentiation. The involvement of estrogens in stimulation of growth of already transformed breast cancer cells in vivo and in vitro accompanied with activation of JNKs prompted us to investigate the role of synthetic estrogens in the regulation of JNK expression... |
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| Descrizione del documento: | Published online: 28 Aug 2009 Gesehen am 25.11.2020 |
| Descrizione fisica: | Online Resource |
| ISSN: | 1473-0766 |
| DOI: | 10.1080/gye.15.2.135.141 |