Synthetic estrogens-mediated activation of JNK intracellular signaling molecule
Signal transduction pathways regulate the transmission of specific signals to the cells from the surface to the nucleus. Activation of protein kinases such as JNKs (c-jun amino-terminal kinase), a subgroup of the mitogen activated protein kinase (MAPK) family, results in regulation of important cell...
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| Hauptverfasser: | , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2009
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| In: |
Gynecological endocrinology
Year: 2001, Jahrgang: 15, Heft: 2, Pages: 135-141 |
| ISSN: | 1473-0766 |
| DOI: | 10.1080/gye.15.2.135.141 |
| Online-Zugang: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1080/gye.15.2.135.141 Verlag, lizenzpflichtig, Volltext: https://www.tandfonline.com/doi/abs/10.1080/gye.15.2.135.141 
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| Verfasserangaben: | S. Prifti, P. Mall, T. Strowitzki and T. Rabe |
| Zusammenfassung: | Signal transduction pathways regulate the transmission of specific signals to the cells from the surface to the nucleus. Activation of protein kinases such as JNKs (c-jun amino-terminal kinase), a subgroup of the mitogen activated protein kinase (MAPK) family, results in regulation of important cellular functions like cell growth and differentiation. The involvement of estrogens in stimulation of growth of already transformed breast cancer cells in vivo and in vitro accompanied with activation of JNKs prompted us to investigate the role of synthetic estrogens in the regulation of JNK expression... |
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| Beschreibung: | Published online: 28 Aug 2009 Gesehen am 25.11.2020 |
| Beschreibung: | Online Resource |
| ISSN: | 1473-0766 |
| DOI: | 10.1080/gye.15.2.135.141 |