Increased CXCL4 expression in hematopoietic cells links inflammation and progression of bone marrow fibrosis in MPN
In primary myelofibrosis (PMF), bone marrow fibrosis is driven by normal stromal cells in the context of hematopoietic stem cells (HSCs) that carry myeloprolife
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| Main Authors: | , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
29 October 2020
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| In: |
Blood
Year: 2020, Volume: 136, Issue: 18, Pages: 2051-2064 |
| ISSN: | 1528-0020 |
| DOI: | 10.1182/blood.2019004095 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1182/blood.2019004095 Verlag, lizenzpflichtig, Volltext: https://ashpublications.org/blood/article/136/18/2051/461599/Increased-CXCL4-expression-in-hematopoietic-cells |
| Author Notes: | Hélène F.E. Gleitz, Aurélien J.F. Dugourd, Nils B. Leimkühler, Inge A.M. Snoeren, Stijn N.R. Fuchs, Sylvia Menzel, Susanne Ziegler, Nicolaus Kröger, Ioanna Triviai, Guntram Büsche, Hans Kreipe, Bella Banjanin, Jessica E. Pritchard, Remco Hoogenboezem, Eric M. Bindels, Neele Schumacher, Stefan Rose-John, Shannon Elf, Julio Saez-Rodriguez, Rafael Kramann, Rebekka K. Schneider |
| Summary: | In primary myelofibrosis (PMF), bone marrow fibrosis is driven by normal stromal cells in the context of hematopoietic stem cells (HSCs) that carry myeloprolife |
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| Item Description: | Gesehen am 26.11.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1528-0020 |
| DOI: | 10.1182/blood.2019004095 |