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Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

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Stig Bojesen, Georgia Chenevix-Trench, Alison Dunning and colleagues report common variants at the TERT-CLPTM1L locus associated with mean telomere length measured in whole blood. They also identify associations at this locus to breast or ovarian cancer susceptibility and report functional studies i...

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Main Authors: Bojesen, Stig Egil (Author) , Chang-Claude, Jenny (Author) , Burwinkel, Barbara (Author) , Marmé, Frederik (Author) , Hein, Rebecca (Author) , Brenner, Hermann (Author) , Hamann, Ute (Author) , Rudolph, Anja (Author) , Nickels, Stefan (Author) , Schneeweiss, Andreas (Author) , Sohn, Christof (Author) , Müller, Heiko (Author) , Arndt, Volker (Author) , Sutter, Christian (Author)
Format: Article (Journal)
Language:English
Published: 27 March 2013
In: Nature genetics
Year: 2013, Volume: 45, Issue: 4, Pages: 371-384
ISSN:1546-1718
DOI:10.1038/ng.2566
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/ng.2566
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/ng.2566
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Author Notes:Stig E. Bojesen, Jenny Chang-Claude, Barbara Burwinkel, Frederik Marme, Rebecca Hein, Hermann Brenner, Ute Hamann, Anja Rudolph, Stefan Nickels, Andreas Schneeweiss, Christof Sohn, Heiko Müller, Volker Arndt, Christian Sutter, und weitere 423
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Summary:Stig Bojesen, Georgia Chenevix-Trench, Alison Dunning and colleagues report common variants at the TERT-CLPTM1L locus associated with mean telomere length measured in whole blood. They also identify associations at this locus to breast or ovarian cancer susceptibility and report functional studies in breast and ovarian cancer tissue and cell lines.
Item Description:Gesehen am 01.12.2020
Physical Description:Online Resource
ISSN:1546-1718
DOI:10.1038/ng.2566

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