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Acute toxicity of normofractionated intensity modulated radiotherapy with simultaneous integrated boost compared to three-dimensional conformal radiotherapy with sequential boost in the adjuvant treatment of breast cancer

Intensity-modulated radiotherapy (IMRT) improves dose homogeneity and late toxicity compared to simple tangential techniques in adjuvant whole-breast radiotherapy for patients with breast cancer. Simultaneous-integrated boost (SIB) radiotherapy shortens the overall treatment time and improves dose h...

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Main Authors: Krug, David (Author) , Köder, Christine (Author) , Häfner, Matthias (Author) , Arians, Nathalie (Author) , Harrabi, Semi B. (Author) , Körber, Stefan A. (Author) , Forster, Tobias (Author) , Schlampp, Ingmar (Author) , Sohn, Christof (Author) , Heil, Jörg (Author) , Hof, Holger (Author) , Hörner-Rieber, Juliane (Author) , Debus, Jürgen (Author)
Format: Article (Journal)
Language:English
Published: 13 October 2020
In: Radiation oncology
Year: 2020, Volume: 15
ISSN:1748-717X
DOI:10.1186/s13014-020-01652-x
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13014-020-01652-x
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Author Notes:David Krug, Christine Köder, Matthias F. Häfner, Nathalie Arians, Semi B. Harrabi, Stefan A. Koerber, Tobias Forster, Ingmar Schlampp, Christof Sohn, Joerg Heil, Holger Hof, Juliane Hörner-Rieber and Jürgen Debus
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Summary:Intensity-modulated radiotherapy (IMRT) improves dose homogeneity and late toxicity compared to simple tangential techniques in adjuvant whole-breast radiotherapy for patients with breast cancer. Simultaneous-integrated boost (SIB) radiotherapy shortens the overall treatment time and improves dose homogeneity. However, prospective randomized trials regarding IMRT with SIB for adjuvant radiotherapy in breast cancer are lacking.
Item Description:Gesehen am 03.12.2020
Physical Description:Online Resource
ISSN:1748-717X
DOI:10.1186/s13014-020-01652-x

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