Quantification of conversion and degradation of circulating angiotensin in rats
The aim of the present study was to quantify with a uniform technique the rates of conversion of ANG I to ANG II in the lung and kidney and the degradation of both peptides to biologically inactive products in the pulmonary, renal, and systemic circulation. We infused the peptides intravenously, int...
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| Main Authors: | , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
1 August 1999
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| In: |
American journal of physiology. Regulatory, integrative and comparative physiology
Year: 1999, Volume: 277, Issue: 2, Pages: R412-R418 |
| ISSN: | 1522-1490 |
| DOI: | 10.1152/ajpregu.1999.277.2.R412 |
| Online Access: | Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1152/ajpregu.1999.277.2.R412 Verlag, lizenzpflichtig, Volltext: https://journals.physiology.org/doi/full/10.1152/ajpregu.1999.277.2.R412 |
| Author Notes: | Johannes Bauer, Heike Berthold, Franz Schaefer, Heimo Ehmke, and Niranjan Parekh |
| Summary: | The aim of the present study was to quantify with a uniform technique the rates of conversion of ANG I to ANG II in the lung and kidney and the degradation of both peptides to biologically inactive products in the pulmonary, renal, and systemic circulation. We infused the peptides intravenously, into the left ventricle, and into the left renal artery of rats and compared their effects on renal blood flow. |
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| Item Description: | Gesehen am 10.12.2020 |
| Physical Description: | Online Resource |
| ISSN: | 1522-1490 |
| DOI: | 10.1152/ajpregu.1999.277.2.R412 |