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1,25(OH)2D3 and dihydrotestosterone interact to regulate proliferation and differentiation of epiphyseal chondrocytes

Growth plate chondrocytes are affected by 1,25(OH)2D3 and androgens, which may critically interact to regulate proliferation and differentiation during the male pubertal growth spurt. We investigated possible interactions of 1,25(OH)2D3 and the non-aromatizable androgen dihydrotestosterone (DHT) in...

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Main Authors: Krohn, Kathrin (Author) , Haffner, Dieter (Author) , Hügel, Ulrike (Author) , Himmele, Rainer (Author) , Klaus, Günter (Author) , Mehls, Otto (Author) , Schaefer, Franz (Author)
Format: Article (Journal)
Language:English
Published: 24 July 2003
In: Calcified tissue international
Year: 2003, Volume: 73, Issue: 4, Pages: 400-410
ISSN:1432-0827
DOI:10.1007/s00223-002-2160-9
Online Access:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00223-002-2160-9
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00223-002-2160-9
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Author Notes:K. Krohn, D. Haffner, U. Hügel, R. Himmele, G. Klaus, O. Mehls, F. Schaefer
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Summary:Growth plate chondrocytes are affected by 1,25(OH)2D3 and androgens, which may critically interact to regulate proliferation and differentiation during the male pubertal growth spurt. We investigated possible interactions of 1,25(OH)2D3 and the non-aromatizable androgen dihydrotestosterone (DHT) in primary chondrocyte cultures from young male rats.
Item Description:Gesehen am 11.12.2020
Physical Description:Online Resource
ISSN:1432-0827
DOI:10.1007/s00223-002-2160-9

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