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1,25(OH)2D3 and dihydrotestosterone interact to regulate proliferation and differentiation of epiphyseal chondrocytes

Growth plate chondrocytes are affected by 1,25(OH)2D3 and androgens, which may critically interact to regulate proliferation and differentiation during the male pubertal growth spurt. We investigated possible interactions of 1,25(OH)2D3 and the non-aromatizable androgen dihydrotestosterone (DHT) in...

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Hauptverfasser: Krohn, Kathrin (VerfasserIn) , Haffner, Dieter (VerfasserIn) , Hügel, Ulrike (VerfasserIn) , Himmele, Rainer (VerfasserIn) , Klaus, Günter (VerfasserIn) , Mehls, Otto (VerfasserIn) , Schaefer, Franz (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 24 July 2003
In: Calcified tissue international
Year: 2003, Jahrgang: 73, Heft: 4, Pages: 400-410
ISSN:1432-0827
DOI:10.1007/s00223-002-2160-9
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00223-002-2160-9
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007/s00223-002-2160-9
Volltext
Verfasserangaben:K. Krohn, D. Haffner, U. Hügel, R. Himmele, G. Klaus, O. Mehls, F. Schaefer
Beschreibung
Zusammenfassung:Growth plate chondrocytes are affected by 1,25(OH)2D3 and androgens, which may critically interact to regulate proliferation and differentiation during the male pubertal growth spurt. We investigated possible interactions of 1,25(OH)2D3 and the non-aromatizable androgen dihydrotestosterone (DHT) in primary chondrocyte cultures from young male rats.
Beschreibung:Gesehen am 11.12.2020
Beschreibung:Online Resource
ISSN:1432-0827
DOI:10.1007/s00223-002-2160-9

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