Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl
We report the clinical course of a prepubertal girl with central diabetes insipidus (DI) and consequent panhypopituitarism evolving over a period of 10 years due to lymphocytic hypophysitis and subsequent germinoma. Two years after the diagnosis of central DI was established, MRI revealed a thickene...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
March 1999
|
| In: |
European journal of pediatrics
Year: 1999, Jahrgang: 158, Heft: 4, Pages: 288-292 |
| ISSN: | 1432-1076 |
| DOI: | 10.1007/s004310051074 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s004310051074
|
| Verfasserangaben: | M. Bettendorf, M. Fehn, J. Grulich-Henn, B. Selle, K. Darge, D.K. Lüdecke, U.E. Heinrich, W. Saeger |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1742823556 | ||
| 003 | DE-627 | ||
| 005 | 20230427190858.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 201215s1999 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s004310051074 |2 doi | |
| 035 | |a (DE-627)1742823556 | ||
| 035 | |a (DE-599)KXP1742823556 | ||
| 035 | |a (OCoLC)1341383807 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Bettendorf, Markus |e VerfasserIn |0 (DE-588)111028876 |0 (DE-627)589912151 |0 (DE-576)30212246X |4 aut | |
| 245 | 1 | 0 | |a Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl |c M. Bettendorf, M. Fehn, J. Grulich-Henn, B. Selle, K. Darge, D.K. Lüdecke, U.E. Heinrich, W. Saeger |
| 264 | 1 | |c March 1999 | |
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 15.12.2020 | ||
| 520 | |a We report the clinical course of a prepubertal girl with central diabetes insipidus (DI) and consequent panhypopituitarism evolving over a period of 10 years due to lymphocytic hypophysitis and subsequent germinoma. Two years after the diagnosis of central DI was established, MRI revealed a thickened pituitary stalk. Later pituitary enlargement and increasing thickening of the pituitary stalk impinging on the optic chiasm required a trans-sphenoidal biopsy which disclosed active hypophysitis with lymphocytic infiltrates and necrosis. High dose dexamethasone treatment only temporarily halted the disease process. Therefore, stereotactic radiation therapy was performed as a rescue treatment and MRI findings almost reversed. However, the subsequent MRI showed multiple intracranial lesions identified histologically as a germinoma and a standard chemotherapy and radiation was performed. | ||
| 700 | 1 | |a Fehn, Marita |e VerfasserIn |0 (DE-588)1223409449 |0 (DE-627)1742751792 |4 aut | |
| 700 | 1 | |a Grulich-Henn, Jürgen |e VerfasserIn |0 (DE-588)1068938595 |0 (DE-627)82305263X |0 (DE-576)428313906 |4 aut | |
| 700 | 1 | |a Selle, Barbara |d 1951- |e VerfasserIn |0 (DE-588)1070468886 |0 (DE-627)823890228 |0 (DE-576)430051735 |4 aut | |
| 700 | 1 | |a Darge, K. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lüdecke, D. K. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Heinrich, Udo |e VerfasserIn |0 (DE-588)1117237176 |0 (DE-627)871328372 |0 (DE-576)478874197 |4 aut | |
| 700 | 1 | |a Saeger, W. |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of pediatrics |d Berlin : Springer Science & Business Media B.V., 1975 |g 158(1999), 4, Seite 288-292 |h Online-Ressource |w (DE-627)684135361 |w (DE-600)2647723-3 |w (DE-576)367395959 |x 1432-1076 |7 nnas |a Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl |
| 773 | 1 | 8 | |g volume:158 |g year:1999 |g number:4 |g pages:288-292 |g extent:5 |a Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s004310051074 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20201215 | ||
| 993 | |a Article | ||
| 994 | |a 1999 | ||
| 998 | |g 1117237176 |a Heinrich, Udo |m 1117237176:Heinrich, Udo |d 910000 |d 910500 |e 910000PH1117237176 |e 910500PH1117237176 |k 0/910000/ |k 1/910000/910500/ |p 7 | ||
| 998 | |g 1068938595 |a Grulich-Henn, Jürgen |m 1068938595:Grulich-Henn, Jürgen |d 910000 |d 910500 |e 910000PG1068938595 |e 910500PG1068938595 |k 0/910000/ |k 1/910000/910500/ |p 3 | ||
| 998 | |g 111028876 |a Bettendorf, Markus |m 111028876:Bettendorf, Markus |d 910000 |d 910500 |e 910000PB111028876 |e 910500PB111028876 |k 0/910000/ |k 1/910000/910500/ |p 1 |x j | ||
| 999 | |a KXP-PPN1742823556 |e 3825682447 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["M. Bettendorf, M. Fehn, J. Grulich-Henn, B. Selle, K. Darge, D.K. Lüdecke, U.E. Heinrich, W. Saeger"]},"language":["eng"],"note":["Gesehen am 15.12.2020"],"recId":"1742823556","person":[{"family":"Bettendorf","role":"aut","given":"Markus","display":"Bettendorf, Markus"},{"given":"Marita","display":"Fehn, Marita","family":"Fehn","role":"aut"},{"given":"Jürgen","display":"Grulich-Henn, Jürgen","family":"Grulich-Henn","role":"aut"},{"family":"Selle","role":"aut","display":"Selle, Barbara","given":"Barbara"},{"given":"K.","display":"Darge, K.","family":"Darge","role":"aut"},{"role":"aut","family":"Lüdecke","given":"D. K.","display":"Lüdecke, D. K."},{"family":"Heinrich","role":"aut","given":"Udo","display":"Heinrich, Udo"},{"display":"Saeger, W.","given":"W.","family":"Saeger","role":"aut"}],"id":{"eki":["1742823556"],"doi":["10.1007/s004310051074"]},"physDesc":[{"extent":"5 S."}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"title":[{"title":"Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl","title_sort":"Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl"}],"origin":[{"dateIssuedDisp":"March 1999","dateIssuedKey":"1999"}],"relHost":[{"corporate":[{"display":"Belgian Association of Pediatric Anesthesiologists","role":"isb"}],"disp":"Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girlEuropean journal of pediatrics","type":{"media":"Online-Ressource","bibl":"periodical"},"titleAlt":[{"title":"Zeitschrift für Kinderheilkunde"}],"part":{"volume":"158","year":"1999","text":"158(1999), 4, Seite 288-292","issue":"4","extent":"5","pages":"288-292"},"language":["ger","eng"],"pubHistory":["121.1975/76 -"],"note":["Fortsetzung der Druck-Ausgabe","Gesehen am 29.05.12","Ungezählte Beil.: Supplement"],"id":{"issn":["1432-1076"],"eki":["684135361"],"zdb":["2647723-3"]},"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"European journal of pediatrics","title":"European journal of pediatrics","subtitle":"official organ of the Belgian Pediatric Association"}],"origin":[{"dateIssuedKey":"1975","publisherPlace":"Berlin ; Dordrecht","publisher":"Springer Science & Business Media B.V.","dateIssuedDisp":"1975-"}],"recId":"684135361"}]} | ||
| SRT | |a BETTENDORFLYMPHOCYTI1999 | ||