tRNA modifications: necessary for correct tRNA-derived fragments during the recovery from stress?

Endonuclease-mediated tRNA fragmentation has been observed in many species suggesting functional importance for tRNA fragments. The size distribution of tRNA-derived fragments indicates the existence of mechanisms that protect tRNAs and their fragments from total degradation by exonucleases. Could p...

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Bibliographic Details
Main Authors: Durdevic, Zeljko (Author) , Schaefer, Matthias R. (Author)
Format: Article (Journal)
Language:English
Published: 11 January 2013
In: Bioessays
Year: 2013, Volume: 35, Issue: 4, Pages: 323-327
ISSN:1521-1878
Online Access:Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/bies.201200158
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Author Notes:Zeljko Durdevic and Matthias Schaefer
Description
Summary:Endonuclease-mediated tRNA fragmentation has been observed in many species suggesting functional importance for tRNA fragments. The size distribution of tRNA-derived fragments indicates the existence of mechanisms that protect tRNAs and their fragments from total degradation by exonucleases. Could post-transcriptional modifications be important for the controlled processing of tRNAs?
Item Description:Gesehen am 05.01.2021
Physical Description:Online Resource
ISSN:1521-1878